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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUBB1
All Species:
18.18
Human Site:
S35
Identified Species:
28.57
UniProt:
Q9H4B7
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B7
NP_110400.1
451
50327
S35
H
G
I
D
L
A
G
S
D
R
G
A
S
A
L
Chimpanzee
Pan troglodytes
Q8WP14
444
49773
T35
H
A
I
N
S
A
G
T
Y
H
G
D
S
H
L
Rhesus Macaque
Macaca mulatta
XP_001082345
451
50234
S35
H
G
I
D
L
A
G
S
D
R
G
A
S
A
L
Dog
Lupus familis
XP_543075
458
50159
G35
H
G
I
D
S
V
G
G
Y
C
G
D
C
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERD7
450
50400
N35
H
G
I
D
P
S
G
N
Y
V
G
D
S
D
L
Rat
Rattus norvegicus
Q6P9T8
445
49782
T35
H
G
I
D
P
T
G
T
Y
H
G
D
S
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511352
452
50925
N35
H
G
I
D
T
N
G
N
Y
H
G
D
S
A
L
Chicken
Gallus gallus
P09207
446
50135
N35
H
G
I
D
I
A
G
N
Y
C
G
N
A
S
L
Frog
Xenopus laevis
P13602
443
49705
S35
H
G
I
D
P
T
G
S
Y
H
G
D
S
D
L
Zebra Danio
Brachydanio rerio
XP_686874
466
52560
A35
H
G
I
N
R
V
G
A
Y
E
G
D
M
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24560
447
50129
A35
H
G
I
D
A
T
G
A
Y
H
G
D
S
D
L
Honey Bee
Apis mellifera
XP_392313
447
50157
T35
H
G
I
D
P
T
G
T
Y
H
G
D
S
D
L
Nematode Worm
Caenorhab. elegans
P41937
444
49782
A35
H
G
I
D
P
T
G
A
Y
N
G
D
S
D
L
Sea Urchin
Strong. purpuratus
XP_791790
447
50098
T35
H
G
I
D
P
T
G
T
Y
H
G
D
S
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P18025
446
49944
R35
H
G
I
D
A
T
G
R
Y
G
G
D
S
D
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.6
98.6
81
N.A.
77.8
78
N.A.
87.6
83.5
77.8
76.1
N.A.
78
77.8
76.7
78.2
Protein Similarity:
100
86.9
99.3
91.4
N.A.
89.1
88.2
N.A.
94.2
91.8
88.2
87.7
N.A.
88.9
88.9
88
88.4
P-Site Identity:
100
46.6
100
53.3
N.A.
53.3
53.3
N.A.
60
53.3
60
40
N.A.
53.3
53.3
53.3
53.3
P-Site Similarity:
100
60
100
53.3
N.A.
66.6
60
N.A.
66.6
80
60
53.3
N.A.
60
60
60
60
Percent
Protein Identity:
N.A.
73.1
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
85.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
14
27
0
20
0
0
0
14
7
27
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
14
0
0
7
0
0
% C
% Asp:
0
0
0
87
0
0
0
0
14
0
0
80
0
60
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
94
0
0
0
0
100
7
0
7
100
0
0
0
0
% G
% His:
100
0
0
0
0
0
0
0
0
47
0
0
0
7
0
% H
% Ile:
0
0
100
0
7
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
14
0
0
0
0
0
0
0
0
0
100
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
14
0
7
0
20
0
7
0
7
0
0
0
% N
% Pro:
0
0
0
0
40
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
7
0
14
0
0
0
0
0
% R
% Ser:
0
0
0
0
14
7
0
20
0
0
0
0
80
7
0
% S
% Thr:
0
0
0
0
7
47
0
27
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
14
0
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
87
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _